Bovine pericardium retail preserved in glutaraldehyde and used as a vascular patch Your Health and Fitness

Jan 14

Bovine pericardium retail preserved in glutaraldehyde and used as a vascular patch

Published: 22 December 2011

Background

In this study we evaluated the performance of bovine pericardium preserved in glutaraldehyde used as a vascular patch. Methods: Fourteen young pigs, six females and eight males, weighting 10.3 – 18.4 kg were used in our study. We implanted three remnants in each pig, two in the abdominal aorta and one was juxtaposed to peritoneum. The smooth face (SF) and rough face (RF) of each remnant were implanted turned to the vessel inner portion and one remnant was juxtaposed to peritoneum. The animals were sacrificed in 4.5 – 8 months after surgery (75 – 109 kg). The remnants were assessed for aorta wall, fibroses formation in inner apposition and calcification related to the face turned to the vessel inner portion. Results: The rough face showed a lower dilatation level compared to the face implanted in adjacent aorta. There was no difference between intensity and/or incidence of graft calcification when the superficies were compared. The bovine pericardium preserved in glutaraldehyde did not show alterations in its structure when implanted with different faces turned to the inner portion of vessel. Conclusion: When turned to the inner portion of the vessel, the rough face of the remnant presented a lower dilatation in relation to the adjacent aorta and a better quality of endothelium layer and was not showed difference between intensity and/or incidence of graft calcification.

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